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Geoffrey Barnes is lead author on study published in the American Journal of Medicine finding new anticoagulants are driving increase in atrial fibrillation treatment and reducing warfarin therapy use.

“The data provides a promising outlook about atrial fibrillation which is known for being undertreated,” says lead author Geoffrey Barnes, M.D., MSc.,  cardiologist at the University of Michigan Health System and researcher at the Institute for Healthcare Policy and Innovation.  “When we don’t treat atrial fibrillation, patients are at risk for stroke. By seeking treatment, patients set themselves up for better outcomes.”

More details can be found here.

Funded by National Institutes of Health

Funding Years: 2011-2016

This proposal seeks to advance our understanding of the role of psychosocial and environmental health risk factors as well as medical care in understanding the large socioeconomic and racial/ethnic disparities in health and the way health changes with age in our society. It does so by proposing to extend to four waves and 15 years of follow-up an ongoing prospective study (known as Americans' Changing Lives) of a nationally representative sample of 3,617 adults aged 25 and over in the coterminous United States, who were first interviewed in 1986, with reinterviews of about 83 percent of the surviving members of the original sample already completed in 1989 and 1994, along with ongoing mortality ascertainment on the full original 1986 sample. A proposed fourth wave would be collected on about 83 percent of the surviving sample (estimated respondents - 2,300 of about 2,800 survivors) in 2001, primarily by telephone and in person as necessary, with mortality ascertainment continuing indefinitely and the hope and intent of reinterviewing surviving respondents again about 20-22.5 years after the baseline interview. The ongoing ACL study has generated a large body of publications both by staff of the ACL project and users of the public use data sets for the first two waves (with the third wave to be archived for public use by the end of 1999). ACL analyses and publications have illuminated to the role of a broad range of psychosocial factors, ranging from health behaviors through stress and adaptive resources to productive activities, in predicting health, changes in health and mortality, and in mediating or explaining socioeconomic differences in health. It has also played a major role in understanding the nature, causes, and consequences of paid and unpaid productive activities over the lifecourse. The proposed continuation and extension of the ACL project will address a number of aims: (1) continuing and enhancing ongoing analysis by extending prospective follow-up to 15 years, allowing for better analysis of- (a) time- varying covariates, (b) the impact of changes in risk factors on changes in health, and (c) potential reciprocal relationships between and among SES, psychosocial risk factors and health; (2) enhancing and improving the measurement of a number of variables already being considered in ongoing analysis, including SES (e.g., improving assessment of wealth), productive activities, religious beliefs and behaviors, and personality or dispositional factors (e.g., hostility, optimism, hopelessness, and John Henryism); (3) adding new measures to ACL 4 or (via archival data) to all waves of data for both medical care and exposures in physical and social environments; and (4) to undertake more focused analysis of racial/ethnic differences in health and explanations of them.

PI(s): Sarah Burgard

Co-I(s): Wen Ye, Michael Elliott, Philippa Clarke, Kenneth Langa

CBSSM Seminar: Stephen Molldrem, PhD Candidate

Thu, July 07, 2016, 3:00pm
Location: 
NCRC Building 16, Conference Rm 266C

Stephen Molldrem, PhD Candidate, American Culture

Title: Collecting and Managing Sexual Orientation and Gender Identity Data in Health Contexts: Bioethical Dilemmas from a Queer Historical Perspective

Abstract: This talk, drawn from dissertation research, historicizes a number of regulatory changes governing the collection and management of sexual orientation and gender identity data in health contexts in the United States that have taken place since 2009. It focuses on a range of less-considered bioethical dilemmas that stem from the introduction of questions about sexual orientation and gender identity into the battery of demographic information collected in certified Electronic Health Record technologies.

Attitudes toward Return of Secondary Results in Genomic Sequencing (Sep-16)

Imagine you are at the doctor’s office because you (or your child) have a serious health condition like heart disease or cancer. To help find out whether any treatment options exist, your doctor suggests that you (or your child) have your genome sequenced.

Genome sequencing may provide information about your (or your child’s) current health condition. However, the genome sequencing could reveal additional and unexpected results not related to the current condition. The doctor wants to know what types of these secondary results you would want to be told.

Funded by NIH - Department of Health and Human Services

Funding Years: 2015-2017

The major goals of this project are to identify the degree to which social disparities exist in physicians' communication about important clinical issues with patients with serious and life-limiting illnesses. This project also studies patient communication behaviors that exacerbate or attenuate those disparities. Results from this research will inform interventions for physicians and patients to promote better communication and thereby reduce or eliminate social disparities in care.

PI(s): Jennifer Griggs

Co-I(s): Masahito Jimbo

Thu, July 14, 2016

A new article in The Conversation authored by CBSSM Co-Director Raymond De Vries and colleague Tom Tomlinson from Michigan State University explores ethical concerns that may arise when patients donate blood and tissue samples to biobanks.

The article highlights results from their national survey, which indicated that respondents were not solely concerned with privacy, but had moral concerns about how their donations could be used in future research.

Wed, May 18, 2016

Reshma Jagsi’s survey of high-achieving physician-scientists published in JAMA, found that nearly a third of women reported experiencing sexual harassment. As women now make up about half of medical school students, the researchers emphasize the importance of recognizing unconscious bias as well as overtly inappropriate behaviors.

1. Reshma Jagsi, Kent A. Griffith, Rochelle Jones, Chithra R. Perumalswami, Peter Ubel, Abigail Stewart. Sexual Harassment and Discrimination Experiences of Academic Medical Faculty. JAMA, 2016; 315 (19): 2120 DOI: 10.1001/jama.2016.2188

Research Topics: 

Raymond De Vries is involved in a new research study led by Akbar Waljee, MD, MSc, which will develop a risk-based strategy to help providers tailor timing of treatments among CHC Veterans to ensure that those who most need urgent therapy get it as quickly as possible.

Using democratic deliberation, Dr. De Vries will engage Veterans to learn their thoughts and preferences about such a strategy, which will help with its implementation in a clinical setting.

Click here for more details.

Mon, January 30, 2017

Kayte Spector-Bagdady has a new commentary out in The Conversation about the law and ethics of research with human biospecimens. It focuses on the recently published revisions to the human subjects research regulations, highlights the debate that ensued from a draft version over its proposal to include nonidentified biospecimens in its definition of "human subject," and summarizes where the final rule landed and possible steps going forward.

Research Topics: 

Panel Discussion: Ethical, Legal, and Social Implications of Genetics and Newborn Screening

Mon, September 25, 2017, 6:00pm
Location: 
Vandenberg Room, Michigan League

Join Joselin Linder, author of “The Family Gene”, and Jodyn Platt, assistant professor in the U-M Medical School in a panel discussion about the ethical, legal, and social implications of genetics and newborn screening. The conversation will be moderated by Kayte Spector-Bagdady, assistant professor in the U-M Medical School and chief of the research ethics service in the Center for Bioethics and Social Sciences in Medicine.

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